The book traces the myriad of scientific breakthroughs over past four millennia, and uncovers the creative processes of discovery and the triumphs or tragedies of the personalities behind them.

Try to imagine life without antibiotics. Without them, we wouldn't live nearly as long as we do. Or before Louis Pasteur discovered that disease came from micro-organisms, and that bacteria could be killed by heat and disinfectants. The idea caused doctors to wash their hands and sterilize their instruments which continues to save millions of lives every year.

The human curiosity continues to thrive, and the 'little globe of sunshine' remains with us, a symbol of those eureka moments that herald scientific breakthroughts.